One way to find the GCF of 16 and 49 is to compare the prime factorization of each number. To find the prime factorization, you can follow the instructions for each number here:
Here is the prime factorization of 16:
And this is the prime factorization of 49:
When you compare the prime factorization of these two numbers, you can see that there are no matching prime factors. When this is the case, it means that there are no common factors between these two numbers. As a result, the GCF of 16 and 49 is 1.
Thus, the GCF of 16 and 49 is: 1